Horticultural Sciences Department

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Dr. Gilles J Basset

Associate Professor

Office:1109 Fifield Hall
Fax:(352) 273 4808

Areas of Research:

  • Biochemical Genetics/Metabolic biochemistry
    Research in our laboratory aims at understanding how plants synthesize redox cofactors that are vital for photosynthesis and respiration. We apply the gained knowledge to enhance the bioenergetics capabilities and nutritional value of plants using synthetic biology.

Educational Background

  • PhD, University of Bordeaux, France (2000).
  • Master of Science Degree in Structural Biochemistry and Molecular Genetics, University of Bordeaux, France (1995)
  • Bachelor of Science Degree in Chemistry and Biology, University of Bordeaux, France (1994)

Teaching Responsibilities

  • Plant Cell and Developmental Biology (PCB6528)

Work and International Experience

  • Associate Professor; Center for Plant Science Innovation, University of Nebraska-Lincoln (2013)
  • Assistant Professor; Center for Plant Science Innovation, University of Nebraska-Lincoln (2007)
  • Chargé de Recherche (Researcher)- National Institute for Agronomic Research (INRA), France (2005)
  • Armament engineer (Mandatory military service)- Atomic Energy Commission (CEA), Paris-Saclay, France (2000)

Recent Honors and Awards

  • National Science Foundation CAREER award (2012)
  • Junior Faculty Recognition for Excellence in Research; Branham Endowment Fund; University of Nebraska-Lincoln (2011)
  • Layman award, University of Nebaska-Lincoln (2009)
  • Ministry of Research and Technology Fellow, France, (1996)

Program Personnel

  • Dr. Eric Soubeyrand (postdoctoral research associate)
  • Ann Bernert (NSF Graduate Research Fellow)
  • Scott Latimer (Graduate student)
  • Dorothea Hopkins (Undergraduate student)
  • Samantha McDonald (Undergraduate student)

Selected Publications

  • Latimer S, Li Y, Nguyen TTH, Soubeyrand E, Fatihi A, Elowsky CG, Block A, Pichersky E, Basset GJ. (2018) Metabolic reconstructions identify plant 3-methylglutaconyl-CoA hydratase that is crucial for branched-chain amino acid catabolism in mitochondria. Plant J. doi: 10.1111/tpj.13955. PubMed PMID: 29742810.

  • Wittkopp TM, Schmollinger S, Saroussi S, Hu W, Zhang W, Fan Q, Gallaher SD, Leonard MT, Soubeyrand E, Basset GJ, Merchant SS, Grossman AR, Duanmu D, Lagarias JC. (2017) Bilin-Dependent Photoacclimation in Chlamydomonas reinhardtii. Plant Cell. 29, 2711-2726.

  • Basset GJ, Latimer S, Fatihi, A, Soubeyrand, E, Block A (2017) Phylloquinone (vitamin K1): Occurrence, biosynthesis and functions. Mini Reviews in Medicinal Chemistry 17, 1028-1038.

  • Strenkert D, Limso CA, Fatihi A, Schmollinger S, Basset GJ, Merchant SS. (2016) Genetically programmed changes in photosynthetic cofactor metabolism in copper-deficient Chlamydomonas. Journal of Biological Chemistry 291, 19118-19131.

  • Fatihi A, Latimer S, Schmollinger S, Block A, Dussault PH, Vermaas WF, Merchant SS, Basset GJ (2015) A dedicated type II NADPH dehydrogenase performs the penultimate step in the biosynthesis of vitamin K1 in Synechocystis and Arabidopsis. The Plant Cell 27, 1730-1741.

  • Block A, Widhalm JR, Fatihi A, Cahoon RE, Wamboldt Y, Elowsky C, Mackenzie SA, Cahoon EB, Chapple C, Dudareva N, Basset GJ (2014) The origin and biosynthesis of the benzenoid moiety of ubiquinone (coenzyme Q) in Arabidopsis. The Plant Cell 26, 1938-1948

  • Block A, Fristedt R, Rogers S, Kumar, J, Barnes B, Barnes J, Elowsky CG, Wamboldt Y, Mackenzie SA, Redding K, Merchant SS, Basset GJ (2013) Functional modeling identifies paralogous solanesyl diphosphate synthases that assemble the side chain of plastoquinone-9 in plastids. Journal of Biological Chemistry 288, 27594-27606

  • Furt F, Allen WJ, Widhalm JR, Madzelan P, Rizzo RC, Basset GJ, Wilson MA (2013) Functional convergence of structurally distinct thioesterases from cyanobacteria and plants involved in phylloquinone biosynthesis. Acta Crystallographica D 69,1876-1888

  • Widhalm JR, Ducluzeau AL, Buller NE, Elowsky CG, Olsen LJ, Basset GJC (2012) Phylloquinone (vitamin K1) biosynthesis in plants: two peroxisomal thioesterases of Lactobacillales origin hydrolyze 1,4-dihydroxy-2-naphthoyl-CoA. The Plant Journal 71, 205-215

  • Fitzpatrick TB, Basset GJ, Borel P,  Carrari F, DellaPenna D, Fraser PD, Hellman H, Osorio-Algar S, Rothan C, Valpuesta V, Caris-Veyrat C, Fernie AR (2012) Vitamin deficiency: Can plant science help? The Plant Cell 24, 395-414

  • Ducluzeau AL, Wamboldt Y, Elowsky CG, Mackenzie SA, Schuurink RC, Basset GJ (2012) Gene network reconstruction identifies the authentic trans-prenyl diphosphate synthase that makes the solanesyl moiety of ubiquinone-9 in Arabidopsis. The Plant Journal 69, 366-375

  • Van Oostende C, Widhalm JR, Furt F, Ducluzeau AL, Basset GJ (2011) Vitamin K1 (phylloquinone): function, enzymes and genes. Advances in Botanical Research 59, 229-261

  • Xu YZ, Arrieta-Montiel MP, Wamboldt YJ, Virdi K,  de Paula WBM, Widhalm JR, Basset GJ, Davila JI, Elthon TE, Elowsky CG, Sato SJ, Clemente TE, Mackenzie SA. (2011) MSH1 is a multi-functional protein in plants that alters mitochondrial and plastid properties and response to high light. The Plant Cell 23, 3428-3441

  • Furt F, van Oostende C, Widhalm JR, Dale MA, Wertz J, Basset GJ (2010) A bimodular oxidoreductase mediates the specific reduction of phylloquinone (vitamin K1) in chloroplasts. The Plant Journal 64, 38-46

  • Widhalm JR, van Oostende C, Furt F, Basset GJ (2009) A dedicated thioesterase of the Hotdog-fold family is required for the biosynthesis of the naphthoquinone ring of vitamin K1. Proceedings of the National Academy of Sciences of the USA 106, 5599-5603